Isotopically Labeled Compounds
Medchemexpress LLC Fmoc-Ser-OH-d3 | 1380308-48-4 | 330.35 | 10 MG
Fmoc-Ser-OH-d3 is the deuterium labeled Fmoc-Ser-OH. It can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC (±)-Nornicotine-d4 | 66148-18-3 | 152.23 | 10 MG
(±)-Nornicotine-d4 is a deuterium labeled (±)-Nornicotine, which is a major metabolite of Nicotine. It acts as a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. This compound has been shown to disrupt β-catenin and ZO-1, induce F-actin depolymerization, and support self-administration behavior.
- Can be used in research for atherosclerosis
- Can be used in research for Alzheimer's disease
- Can be used in research for schizophrenia
Medchemexpress LLC Undecanoic acid-d21 | 60658-40-4 | 207.42 | 5 MG
Undecanoic acid-d21 is a deuterium-labeled monocarboxylic acid known for its antifungal properties. It inhibits the production of exocellular keratinase, lipase, and the biosynthesis of several phospholipids in T. rubrum. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled undecanoic acid
- Monocarboxylic acid with antifungal properties
- Inhibits exocellular keratinase and lipase
- Inhibits biosynthesis of phospholipids in T. rubrum
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 3-Methyl-2-oxobutanoic acid-13C4,d4 sodium | 1185115-88-1 | 146.09 | 10 MG
Sodium 3-methyl-2-oxobutanoate-13C4,d4 is a deuterium and 13C labeled form of Sodium 3-methyl-2-oxobutanoate. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for use as tracers during drug development. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium and 13C labeled compound
- Used as tracers for quantitation in drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Piperidin-4-ol-d5 | 1219799-35-5 | 106.18 | 10 MG
Piperidin-4-ol-d5 is a deuterium-labeled form of Piperidin-4-ol. Stable heavy isotopes, including hydrogen and carbon, are incorporated into drug molecules for various purposes, primarily as tracers for quantitation during drug development. Deuteration has shown the potential to influence the pharmacokinetic and metabolic profiles of drugs. Please note that the accuracy of these methods has not been independently confirmed by MCE and are for reference only.
- Deuterium-labeled Piperidin-4-ol
- Contains stable heavy isotopes of hydrogen, carbon, and other elements
- Suitable for use as tracers in drug development for quantitation
- May influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Arachidic acid-d3 (Icosanoic acid-d3) | 202480-70-4 | 315.55 | 10 MG
Arachidic acid-d3 is the deuterium labeled Arachidic acid. Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. It can be found in human organisms from plasma phospholipid, fish, cannabis, and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide can be used for anti-cancer drug delivery research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Piperidin-4-ol-d4 | 1014695-51-2 | 105.17 | 10 MG
Piperidin-4-ol-d4 is the deuterium labeled Piperidin-4-ol. For research use only. This compound can be used as a tracer, or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Piperidin-4-ol-d4 | 1014695-51-2 | 105.17 | 5 MG
Piperidin-4-ol-d4 is the deuterium labeled Piperidin-4-ol. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes incorporated into drug molecules.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 1-Undecanol-d23 (undecyl alcohol-d23) | 349553-88-4 | 195.45 | 10 MG
1-Undecanol-d23 (Undecyl alcohol-d23) is a deuterium-labeled version of 1-Undecanol, which is produced from the degradation of 2-tridecanone by Pseudomonas bacteria. It has been observed to enhance the attraction of *Grapholita molesta* to sex pheromone traps. This compound is suitable for use as a tracer or an internal standard in quantitative analysis.
- Can be utilized as a tracer
- Serves as an internal standard for quantitative analysis
- Compatible with NMR, GC-MS, or LC-MS techniques
- Stable heavy isotope for drug development studies
Medchemexpress LLC Indole-d7 | 73509-20-3 | 124.19 | 50 MG
Indole-d7 is a deuterium-labeled form of Indole, which is an endogenous metabolite. It serves as a tracer and an internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes, like deuterium, into drug molecules is primarily used for quantitation during drug development processes, with potential effects on pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeling can affect pharmacokinetic and metabolic profiles of drugs
Cayman Chemical TrIclabendazole-13C-d3 5mg
An internal standard for the quantification of triclabendazole by GC- or LC-MS
Cambridge Isotope Laboratories Estradiol (2 4 16 16-D4 95-97%) 5 mg
Estradiol (2 4 16 16-D4 95-97%) 5 mg
Revvity Health Sciences Inc Iodine-125 Radionuclide, 5mCi, Specific Activity: ~17Ci/mg, 10-5M NaOH (pH 8-11)
Iodine-125 Radionuclide, 5mCi, Specific Activity: ~17Ci/mg, 10-5M NaOH (pH 8-11)
TARGETMOL CHEMICALS INC Sphingosine-1-phosphate 1MG
Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, and GPR12. As an intracellular second messenger, it mobilizes Ca2+ and acts as an extracellular ligand for G-protein coupled receptors. This important lipid mediator is generated from sphingosine or other membrane phospholipids. Purity 98.66%